skinbetter science™ AlphaRet Overnight Cream
skinbetter science™ AlphaRet Overnight Cream
Experience the transformative power of the #1 dermatologist-recommended retinoid brand.*
AlphaRet Overnight Cream is a clinically validated prescription-strength retinoid that fights lines while it hydrates skin for visible results in 4 weeks.** Tested even on retinoid-sensitive users to be suitable for nightly use. ***
Why You'll Love It: Helps improve the appearance of fine lines and wrinkles, refines the look of uneven skin tone and texture, and improves skin hydration and visible redness.
All skinbetter science products are dermatologist tested, non-comedogenic, paraben free, fragrance free, dye free, and cruelty free.
*Among non-prescription brands sold by physicians or medical practices, in addition to other outlets or retailers. Blinded nationwide survey of dermatologists 2025. Responding dermatologists may have sales relationships with one or more medical aesthetic brands.
**A 12-week, split-face, randomized, dermatologist-led clinical study in participants with mild-to-severe photoaging (N=48) vs 0.025% tretinoin
***A 12-week multicenter, dermatologist-led clinical study evaluated nightly use of AlphaRet Overnight Cream in participants with self-identified retinoid sensitivity and mild-to-moderate photoaging. (N=56)
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Features & Benefits
Features & Benefits
AlphaRet Overnight Cream is an advanced nighttime retinoid treatment formulated to visibly improve signs of aging with minimal irritation.
- Helps reduce the appearance of fine lines and wrinkles
- Improves uneven skin tone and texture
- Promotes smoother, firmer and more resilient-looking skin
- Helps reduce visible redness
- Boosts hydration and supports the skin’s moisture barrier
- Provides antioxidant protection against free radicals
- Patented AlphaRet® Technology combines a retinoid with an alpha hydroxy acid
- Visible results may be seen in as little as four weeks
- Suitable for all skin types, including retinoid-sensitive skin
- Dermatologist tested and non-comedogenic
How to Use
How to Use
Use once daily in the evening. Apply a thin, even layer to clean, dry skin, avoiding the eye area. Follow with the remaining products in your nighttime skincare routine.
Apply a broad-spectrum sunscreen every morning, as this product may increase sensitivity to the sun. If you are new to retinoids or have sensitive skin, consult your skincare provider for personalized recommendations.
Ingredients
Ingredients
Key Ingredients:
- AlphaRet® Technology: Combines a retinoid with lactic acid to support skin renewal with improved tolerability.
- Glycolic Acid: Helps refine uneven texture and enhance the performance of AlphaRet.
- Peptide Blend: Helps improve the appearance of wrinkles, firmness and resiliency.
- Ceramides, Squalane, Niacinamide and Hyaluronic Acid: Hydrate the skin and support its moisture barrier.
- Allantoin, Glycyrrhetinic Acid, Bisabolol and Green Tea Extract: Help soothe the skin and reduce visible redness.
- Vitamins C and E and Coenzyme Q10: Provide antioxidant protection.
Full Ingredient List:
Aqua/Water, Sodium Glycolate, Glycolic Acid, Cetearyl Olivate, Pentylene Glycol, Cyclopentasiloxane, Isohexadecane, Sorbitan Olivate, Tetrahexyldecyl Ascorbate, Glycerin, Ceresin, Glycol Palmitate, Butylene Glycol, Niacinamide, Squalane, Methyl Gluceth-20, Ethyl Lactyl Retinoate, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide NP, Hyaluronic Acid, Ubiquinone, Tocopherol, Bisabolol, Tocopheryl Acetate, Superoxide Dismutase, Butyrospermum Parkii (Shea) Butter, Allantoin, Glycyrrhetinic Acid, Sodium PCA, Panthenol, Camellia Sinensis Leaf Extract, Portulaca Oleracea Extract, Linoleic Acid, Cholesterol, Linolenic Acid, Magnesium Aluminum Silicate, Dimethyl Isosorbide, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Steareth-2, Hydroxyethylcellulose, Acacia Senegal Gum, Xanthan Gum, Hydrated Silica, Carbomer, Polysorbate 20, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol, Titanium Dioxide (CI 77891).
Additional Information
Additional Information
- Recommended use: Evening
- Best for: Fine lines, wrinkles, photodamage, uneven tone, rough texture, dryness and visible redness
- Skin types: All skin types
- Free from parabens, fragrance and dyes
- Cruelty-free
- Packaged in an airless, twist-up pump to help preserve the formula
Sunburn Alert: This product contains an alpha hydroxy acid that may increase sun sensitivity. Use sunscreen, wear protective clothing and limit sun exposure while using this product and for one week afterward.
Pregnancy Warning: This product contains a topical retinoid. Consult your physician before use if you are pregnant, nursing or planning to become pregnant.
Ingredient formulations may change. Refer to the product packaging for the most current ingredient list.




